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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 13.94
Human Site: S700 Identified Species: 19.17
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S700 T I C S L V E S Q K Q C G N L
Chimpanzee Pan troglodytes XP_507923 1056 119132 S700 T I C S L V E S Q K Q C G N L
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 R519 D L H S K L D R K K A V D Q H
Dog Lupus familis XP_534964 1334 149091 S982 T V S S L A E S Q K L C E N L
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S699 T V S S L V E S Q K L C G D L
Rat Rattus norvegicus O55165 796 89797 Y462 L E K N M E N Y L Q E Q K E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 L681 K D K E V I Q L K E R D R K R
Frog Xenopus laevis P28025 1060 119314 I693 S S S A L S S I Q S E Y E S L
Zebra Danio Brachydanio rerio NP_775368 955 106984 L621 Q D A Q N S I L E I L D E H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 L705 S L P D A E E L Q N L Q E E L
Honey Bee Apis mellifera XP_623508 706 80766 E372 A L L Q E Y I E E I E R L K K
Nematode Worm Caenorhab. elegans P46873 699 78760 A365 P G A V G V G A P A Q D A F S
Sea Urchin Strong. purpuratus P46872 699 78679 E365 R E F Q K E I E E L K K Q I S
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 V710 A V E T A R S V S K V I V N F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 T689 T Q E M S E Y T S T F F Q K L
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 K744 N Q Q L A E M K R Y F Q D H V
Red Bread Mold Neurospora crassa P48467 928 102392 I594 Q L D A L F E I S S A G D A I
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 13.3 66.6 N.A. 73.3 0 N.A. N.A. 0 20 0 N.A. 20 0 13.3 0
P-Site Similarity: 100 100 40 73.3 N.A. 86.6 26.6 N.A. N.A. 40 46.6 13.3 N.A. 33.3 20 20 13.3
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 13.3 N.A. N.A. 13.3 0 13.3
P-Site Similarity: 26.6 N.A. N.A. 20 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 12 18 6 0 6 0 6 12 0 6 6 0 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 24 0 0 0 % C
% Asp: 6 12 6 6 0 0 6 0 0 0 0 18 18 6 0 % D
% Glu: 0 12 12 6 6 30 36 12 18 6 18 0 24 12 0 % E
% Phe: 0 0 6 0 0 6 0 0 0 0 12 6 0 6 6 % F
% Gly: 0 6 0 0 6 0 6 0 0 0 0 6 18 0 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 0 12 6 % H
% Ile: 0 12 0 0 0 6 18 12 0 12 0 6 0 6 6 % I
% Lys: 6 0 12 0 12 0 0 6 12 36 6 6 6 18 12 % K
% Leu: 6 24 6 6 36 6 0 18 6 6 24 0 6 0 42 % L
% Met: 0 0 0 6 6 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 6 6 0 6 0 0 6 0 0 0 24 0 % N
% Pro: 6 0 6 0 0 0 0 0 6 0 0 0 0 0 0 % P
% Gln: 12 12 6 18 0 0 6 0 36 6 18 18 12 6 0 % Q
% Arg: 6 0 0 0 0 6 0 6 6 0 6 6 6 0 12 % R
% Ser: 12 6 18 30 6 12 12 24 18 12 0 0 0 6 12 % S
% Thr: 30 0 0 6 0 0 0 6 0 6 0 0 0 0 0 % T
% Val: 0 18 0 6 6 24 0 6 0 0 6 6 6 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 6 6 6 0 6 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _